Sertraline Tablets
Formulated to alleviate major depressive disorder to support mental wellbeing.
Strengths: 25 · 50 · 100mg
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Medicine details
- Alternative names
Lustral
- Therapeutic class
Selective Serotonin Reuptake Inhibitor (SSRI)
- Pharmacological class
SSRI
- Known off-label uses
premature ejaculation
- Minor side effects
nausea; diarrhoea; insomnia
- Moderate side effects
dizziness; somnolence; sexual dysfunction
- Dosage forms
Film-coated tablet
- Administration route
Oral use
- Patient summary
Formulated to alleviate major depressive disorder to support mental wellbeing.
- Prescription status
POM
- Manufacturer
Pfizer
- Onset Time
2–4 weeks
- Duration
6–12 months
- Storage instructions
Store in a cool, dry place away from direct sunlight.
- Drug interactions
alcohol; st. john's wort; aspirin
- Age restrictions
Used with caution in adolescents.
Contraindications
hypersensitivity to sertraline; concurrent use of MAO inhibitors; concurrent use of pimozide
Precautions and warnings
monitor for worsening mood or suicidal ideation; avoid rapid discontinuation; caution in epilepsy
Serious side effects
serotonin syndrome — requires immediate medical attention; suicidal ideation — requires immediate medical attention
Mechanism of action
Sertraline inhibits the reuptake of serotonin (5-HT) into presynaptic neurons. By increasing the availability of serotonin in the synaptic cleft, it enhances serotonergic transmission, which regulates mood.
Pregnancy and breastfeeding
Pregnancy: Use only if expected benefit outweighs the risks to the fetus. Breastfeeding: Use with caution; monitor infant closely.
Sertraline Tablets
Formulated to alleviate major depressive disorder to support mental wellbeing.
Editorial Notes
- Active ingredient(s): Sertraline
- Listed indication(s): Major Depressive Disorder, Panic Disorder, Obsessive-compulsive Disorder
Usually available as
- 270 tablets - 25 mg1227-25-mg-14613
- 120 tablets - 50 mg1227-50-mg-14618
- 120 tablets - 100 mg1227-100-mg-14625