Losartan Tablets

Utilized to target high blood pressure, formulated to support cardiovascular health by relaxing blood vessels and effectively managing long-term hypertension.

Strengths: 25 · 50 · 100mg

Heart & Blood Pressure icon Heart & Blood Pressure Losartan icon Losartan

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Medicine details

Conditions
Alternative names

Cozaar

Therapeutic class

angiotensin II receptor antagonist

Pharmacological class

sartan

Contraindications

severe hepatic impairment; second and third trimesters of pregnancy

Precautions and warnings

monitor potassium levels; stay hydrated

Minor side effects

dizziness; fatigue

Moderate side effects

hypotension; hyperkalaemia

Dosage forms

Film-coated tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Merck Sharp & Dohme

Onset Time

1–2 weeks

Duration

24 hours

Storage instructions

Store below 30°C.

Drug interactions

potassium supplements; diuretics; lithium

Age restrictions

Not for children under 6 years.

Pregnancy and breastfeeding

Pregnancy: contra-indicated. Breastfeeding: not recommended.

Serious side effects

angioedema — requires immediate medical attention; anaphylaxis — requires immediate medical attention

Patient summary

Utilized to target high blood pressure, formulated to support cardiovascular health by relaxing blood vessels and effectively managing long-term hypertension.

Mechanism of action

Losartan is an angiotensin II receptor antagonist. It selectively blocks the binding of angiotensin II to the AT1 receptor, found in many tissues such as vascular smooth muscle. This blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II, lowering blood pressure.

Losartan Tablets

Utilized to target high blood pressure, formulated to support cardiovascular health by relaxing blood vessels and effectively managing long-term hypertension.

Editorial Notes

  • Active ingredient(s): Losartan
  • Listed indication(s): Hypertension, Diabetic Nephropathy

Usually available as

  • 180 tablets - 25 mg1163-25-mg-13740
  • 180 tablets - 50 mg1163-50-mg-13746
  • 120 tablets - 100 mg1163-100-mg-13751