Cozaar

developed to manage hypertension by blocking the angiotensin II receptor.

Strengths: 25 · 50 · 100mg

Medicine details

Therapeutic class

Angiotensin II Receptor Antagonist

Pharmacological class

Sartan

Known off-label uses

heart failure

Contraindications

pregnancy; severe hepatic impairment

Precautions and warnings

monitor potassium levels; monitor blood pressure

Minor side effects

dizziness; fatigue

Moderate side effects

hypotension; hyperkalaemia

Dosage forms

Film-coated tablet

Administration route

Oral use

Patient summary

developed to manage hypertension by blocking the angiotensin II receptor.

Prescription status

POM

Manufacturer

MSD

Onset Time

1–2 weeks

Duration

24 hours

Storage instructions

Store at room temperature.

Drug interactions

potassium supplements; lithium

Age restrictions

Use with caution in children.

Pregnancy and breastfeeding

Contraindicated in pregnancy.

Serious side effects

angioedema — requires immediate medical attention; renal failure — requires immediate medical attention

Mechanism of action

Losartan is an angiotensin II receptor antagonist that inhibits the vasoconstrictive and aldosterone-secreting effects of angiotensin II, thereby lowering blood pressure.

Cozaar

developed to manage hypertension by blocking the angiotensin II receptor.

Editorial Notes

  • Active ingredient(s): Losartan
  • Listed indication(s): Hypertension, Diabetic Nephropathy

Usually available as

  • 180 tablets - 25 mg27-25-mg-2586
  • 90 tablets - 50 mg27-50-mg-2591
  • 90 tablets - 100 mg27-100-mg-2597