Isotretinoin Capsules

This powerful retinoid is formulated to target severe acne, utilized to alleviate skin inflammation and to mitigate the occurrence of scarring.

Strengths: 10 · 20mg

Medicine details

Alternative names

Roaccutane; Retinad

Therapeutic class

Retinoid

Pharmacological class

Retinoid

Minor side effects

dry skin; chapped lips; dry eyes

Moderate side effects

myalgia; joint pain; headache

Dosage forms

Capsule, soft

Administration route

Oral use

Prescription status

POM

Manufacturer

Roche

Onset Time

2–4 weeks

Duration

16–24 weeks

Storage instructions

Store below 25°C, protect from light and moisture.

Drug interactions

Vitamin A; Tetracyclines

Age restrictions

Used with caution in adolescents.

Contraindications

pregnancy; breastfeeding; hepatic impairment; hypervitaminosis A; elevated blood lipids

Precautions and warnings

avoid sun exposure; do not donate blood during treatment; regular liver function monitoring required

Serious side effects

depression — requires immediate medical attention; suicidal ideation — requires immediate medical attention; pancreatitis — requires immediate medical attention

Patient summary

This powerful retinoid is formulated to target severe acne, utilized to alleviate skin inflammation and to mitigate the occurrence of scarring.

Mechanism of action

Isotretinoin is a retinoid that reduces sebaceous gland size and inhibits sebaceous gland activity, effectively decreasing sebum production and keratinization in the skin.

Pregnancy and breastfeeding

Pregnancy: Highly teratogenic; must use strict contraception. Breastfeeding: Contraindicated.

Isotretinoin Capsules

This powerful retinoid is formulated to target severe acne, utilized to alleviate skin inflammation and to mitigate the occurrence of scarring.

Editorial Notes

  • Active ingredient(s): Isotretinoin
  • Listed indication(s): Severe Cystic Acne

Usually available as

  • 90 tablets - 10 mg1172-10-mg-13886
  • 90 tablets - 20 mg1172-20-mg-13891