Flunarizine Tablets

Intended to support migraine prophylaxis and developed to alleviate vertigo.

Strengths: 5 · 10mg

Medicine details

Alternative names

Sibelium

Therapeutic class

Calcium Channel Blocker

Pharmacological class

Piperazine derivative

Contraindications

history of depression; extrapyramidal symptoms; parkinson's disease

Precautions and warnings

may cause drowsiness; monitor weight gain; include regular breaks in treatment

Minor side effects

somnolence; weight gain; fatigue

Moderate side effects

depression; extrapyramidal disorder; insomnia

Serious side effects

parkinsonism — requires immediate medical attention

Dosage forms

Tablet

Administration route

Oral use

Patient summary

Intended to support migraine prophylaxis and developed to alleviate vertigo.

Prescription status

POM

Manufacturer

Janssen-Cilag

Onset Time

2–4 weeks

Duration

Ongoing prophylaxis

Storage instructions

Store below 25°C, away from light and moisture.

Drug interactions

alcohol; anticonvulsants

Age restrictions

Consult physician for use in elderly.

Pregnancy and breastfeeding

Use only if strictly necessary.

Mechanism of action

Flunarizine prevents cellular calcium overload by blocking calcium channels, which helps stabilize vascular smooth muscle and nerve cells against hypoxia and excessive vasoconstriction.

Flunarizine Tablets

Intended to support migraine prophylaxis and developed to alleviate vertigo.

Editorial Notes

  • Active ingredient(s): Flunarizine
  • Listed indication(s): Migraine Prophylaxis, Vertigo

Usually available as

  • 180 tablets - 5 mg382-5-mg-15063
  • 180 tablets - 10 mg382-10-mg-15058