Sibelium
utilized to alleviate migraine symptoms by blocking calcium influx.
Strengths: 5 · 10mg
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Medicine details
- Conditions
- Therapeutic class
Calcium channel blocker
- Pharmacological class
Calcium channel blocker
- Contraindications
hypersensitivity to flunarizine; history of depression; parkinsonian symptoms
- Precautions and warnings
may cause drowsiness; may cause weight gain
- Minor side effects
fatigue; drowsiness; weight gain
- Moderate side effects
insomnia; depression
- Serious side effects
extrapyramidal symptoms — requires immediate medical attention
- Dosage forms
Tablet
- Administration route
Oral use
- Patient summary
utilized to alleviate migraine symptoms by blocking calcium influx.
- Prescription status
POM
- Onset Time
4–8 weeks
- Duration
24 hours
- Storage instructions
Store below 25°C, away from moisture.
- Drug interactions
alcohol; sedatives
- Age restrictions
Not recommended for children.
- Pregnancy and breastfeeding
Pregnancy: Not recommended. Breastfeeding: Not recommended.
Mechanism of action
Flunarizine prevents the contraction of vascular smooth muscle, reducing the frequency and severity of recurring migraine headaches by stabilizing cell membranes and preventing cerebral vasospasm.
Sibelium
utilized to alleviate migraine symptoms by blocking calcium influx.
Editorial Notes
- Active ingredient(s): Flunarizine
- Listed indication(s): Migraine Prophylaxis
Usually available as
- 180 tablets - 5 mg383-5-mg-15068
- 180 tablets - 10 mg383-10-mg-15073