Duloxetine Capsules
Formulated to target major depressive symptoms; indicated to support mental health and alleviate neuropathic pain.
Strengths: 20 · 30 · 40 · 60mg
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Medicine details
- Alternative names
Cymbalta; Yentreve
- Therapeutic class
Serotonin-Norepinephrine Reuptake Inhibitor
- Pharmacological class
SNRI
- Precautions and warnings
risk of suicidal thinking; monitor blood pressure
- Minor side effects
nausea; dry mouth; dizziness; fatigue
- Moderate side effects
insomnia; anxiety; somnolence
- Dosage forms
Gastro-resistant capsule, hard
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Eli Lilly
- Onset Time
2–4 weeks
- Duration
long-term
- Storage instructions
Store below 25°C.
- Drug interactions
alcohol; st. john's wort; blood thinners
- Age restrictions
Not recommended for children under 18.
- Pregnancy and breastfeeding
Pregnancy: use with caution. Breastfeeding: not recommended.
Contraindications
uncontrolled hypertension; liver disease; concurrent monoamine oxidase inhibitors
Serious side effects
serotonin syndrome — requires immediate medical attention; hypertensive crisis — requires immediate medical attention
Patient summary
Formulated to target major depressive symptoms; indicated to support mental health and alleviate neuropathic pain.
Mechanism of action
A selective serotonin and norepinephrine reuptake inhibitor. It increases the extracellular levels of serotonin and norepinephrine in the synaptic cleft, improving neurotransmission and alleviating symptoms.
Duloxetine Capsules
Formulated to target major depressive symptoms; indicated to support mental health and alleviate neuropathic pain.
Editorial Notes
- Active ingredient(s): Duloxetine
- Listed indication(s): Major Depressive Disorder, Generalized Anxiety Disorder, Diabetic Peripheral Neuropathic Pain
Usually available as
- 120 tablets - 20 mg1372-20-mg-16454
- 60 tablets - 30 mg1372-30-mg-16458
- 60 tablets - 40 mg1372-40-mg-16463