Venlafaxine Tablets

Developed for depression to address emotional symptoms.

Strengths: 37.5 · 75mg

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Medicine details

Conditions
Alternative names

Efexor

Therapeutic class

Serotonin-Norepinephrine Reuptake Inhibitor (SNRI)

Pharmacological class

SNRI

Minor side effects

nausea; dry mouth; sweating; headache

Moderate side effects

insomnia; dizziness; anorexia; sexual dysfunction

Dosage forms

Tablet; Prolonged-release capsule, hard

Administration route

Oral use

Patient summary

Developed for depression to address emotional symptoms.

Prescription status

POM

Manufacturer

Pfizer

Onset Time

2–4 weeks

Duration

24 hours

Storage instructions

Store below 25°C in a dry place.

Drug interactions

St. John's Wort; MAO inhibitors; Alcohol

Age restrictions

Not for patients under 18.

Contraindications

uncontrolled hypertension; concurrent use of monoamine oxidase inhibitors; cardiac arrhythmias

Precautions and warnings

may increase blood pressure; do not stop treatment abruptly; increased risk of suicidal thoughts in early treatment

Serious side effects

serotonin syndrome — requires immediate medical attention; hyponatraemia — requires immediate medical attention

Mechanism of action

Venlafaxine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and a weak inhibitor of dopamine reuptake. By increasing the levels of these neurotransmitters in the synaptic cleft, it helps sustain balanced mood and cognitive response.

Pregnancy and breastfeeding

Pregnancy: Discuss risks with doctor. Breastfeeding: Excreted in milk; monitor infant closely.

Venlafaxine Tablets

Developed for depression to address emotional symptoms.

Editorial Notes

  • Active ingredient(s): Venlafaxine
  • Listed indication(s): Major Depressive Disorder, Generalized Anxiety Disorder

Usually available as

  • 120 tablets - 37.5 mg1318-37-5-mg-15756
  • 90 tablets - 75 mg1318-75-mg-15763