Capecitabine Tablets
Utilized to target malignant cell proliferation, this chemotherapy agent is indicated to support the management of advanced colorectal, breast, and gastric carcinomas.
Strengths: 500mg
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Medicine details
- Alternative names
Xeloda
- Therapeutic class
Antineoplastic agent
- Pharmacological class
Fluoropyrimidine
- Precautions and warnings
monitor for hand-foot syndrome; maintain hydration; report diarrhoea immediately
- Minor side effects
diarrhoea; nausea; fatigue; hand-foot syndrome
- Moderate side effects
stomatitis; abdominal pain; anorexia
- Dosage forms
Film-coated tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Roche
- Onset Time
variable
- Duration
variable
- Storage instructions
Store below 30°C in a dry place.
- Drug interactions
phenytoin; warfarin; folinic acid
- Age restrictions
Adult use only.
- Pregnancy and breastfeeding
Must not be used during pregnancy as it may cause foetal harm.
Contraindications
hypersensitivity to capecitabine; severe renal impairment; pregnancy; breastfeeding; dihydropyrimidine dehydrogenase deficiency
Serious side effects
severe dehydration — requires immediate medical attention; myelosuppression — requires immediate medical attention; cardiotoxicity — requires immediate medical attention
Patient summary
Utilized to target malignant cell proliferation, this chemotherapy agent is indicated to support the management of advanced colorectal, breast, and gastric carcinomas.
Mechanism of action
Capecitabine is a prodrug that is enzymatically converted to 5-fluorouracil in the body. It selectively targets tumour cells, interfering with DNA synthesis and preventing rapidly dividing cells from multiplying.
Capecitabine Tablets
Utilized to target malignant cell proliferation, this chemotherapy agent is indicated to support the management of advanced colorectal, breast, and gastric carcinomas.
Editorial Notes
- Active ingredient(s): Capecitabine
- Listed indication(s): Colorectal Cancer, Breast Cancer, Gastric Cancer
Available option
- 100 tablets - 500 mg1353-500-mg-16280