Aromasin

Developed to target oestrogen production and indicated to support cancer treatment, this inhibitor is utilized to address hormone-sensitive malignancies.

Strengths: 25mg

Medicine details

Conditions
Alternative names

exemestane generics

Therapeutic class

Aromatase inhibitor

Pharmacological class

Steroidal aromatase inactivator

Minor side effects

hot flushes; fatigue; nausea

Moderate side effects

insomnia; arthralgia; alopecia

Dosage forms

Tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Pfizer

Onset Time

2–3 days

Duration

daily

Storage instructions

Store at room temperature, out of reach of children.

Drug interactions

oestrogen-containing therapies; st. john's wort

Age restrictions

Not for children.

Pregnancy and breastfeeding

Pregnancy: Contraindicated. Breastfeeding: Do not use.

Contraindications

pre-menopausal endocrine status; hypersensitivity to exemestane; severe renal impairment; severe hepatic impairment

Precautions and warnings

monitor bone mineral density; regular blood monitoring required; not for pre-menopausal women

Serious side effects

osteoporosis — requires immediate medical attention; pathological fractures — requires immediate medical attention; severe hepatitis — requires immediate medical attention

Patient summary

Developed to target oestrogen production and indicated to support cancer treatment, this inhibitor is utilized to address hormone-sensitive malignancies.

Mechanism of action

Exemestane is a steroidal aromatase inactivator that prevents the conversion of androgens into oestrogens in peripheral tissues. By reducing circulating oestrogen levels, it inhibits the growth of hormone-dependent breast carcinoma.

Aromasin

Developed to target oestrogen production and indicated to support cancer treatment, this inhibitor is utilized to address hormone-sensitive malignancies.

Editorial Notes

  • Active ingredient(s): Exemestane
  • Listed indication(s): Breast Cancer

Available option

  • 30 tablets - 25 mg1439-25-mg-17320