Imipramine Tablets
Developed to target depressive symptoms, indicated to alleviate clinical mood disorders and to support mood regulation.
Strengths: 25 · 50 · 75mg
Where to Check Availability
Medicine details
- Alternative names
Tofranil
- Therapeutic class
Tricyclic antidepressant
- Pharmacological class
TCA
- Known off-label uses
neuropathic pain
- Contraindications
recent myocardial infarction; heart block; concurrent use of mao inhibitors
- Precautions and warnings
may impair alertness; regular cardiovascular monitoring advised
- Minor side effects
dry mouth; drowsiness; blurred vision
- Moderate side effects
constipation; urinary retention; orthostatic hypotension
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Tillotts Pharma
- Onset Time
2–4 weeks
- Duration
8–12 hours
- Storage instructions
Store in a cool, dry environment.
- Drug interactions
alcohol; mao inhibitors; adrenaline
- Age restrictions
Use with caution in children (enuresis) and elderly.
Serious side effects
cardiac arrhythmia — requires immediate medical attention; seizures — requires immediate medical attention
Patient summary
Developed to target depressive symptoms, indicated to alleviate clinical mood disorders and to support mood regulation.
Mechanism of action
Imipramine inhibits the reuptake of both serotonin and norepinephrine in the synaptic cleft, increasing their availability to improve neurotransmission and alleviate mood symptoms.
Pregnancy and breastfeeding
Pregnancy: Use only if absolutely necessary. Breastfeeding: Pass into breast milk; not recommended.
Imipramine Tablets
Developed to target depressive symptoms, indicated to alleviate clinical mood disorders and to support mood regulation.
Editorial Notes
- Active ingredient(s): Imipramine
- Listed indication(s): Major Depressive Disorder, Nocturnal Enuresis
Usually available as
- 360 tablets - 25 mg1216-25-mg-14420
- 120 tablets - 75 mg1216-75-mg-14427