Verampil
Utilized to manage hypertension, formulated to target calcium channels and support stable blood pressure control.
Strengths: 40 · 120mg
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Medicine details
- Alternative names
Cordilox; Securon
- Therapeutic class
Calcium Channel Blocker
- Pharmacological class
Calcium Channel Blocker
- Known off-label uses
cluster headache
- Minor side effects
headache; dizziness; constipation; fatigue
- Moderate side effects
peripheral oedema; hypotension; bradycardia
- Dosage forms
Film-coated tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Mylan
- Onset Time
1–2 hours
- Duration
6–8 hours
- Storage instructions
Store at room temperature in a dry place.
- Drug interactions
alcohol; grapefruit; beta blockers
- Age restrictions
Not recommended for children.
Contraindications
hypersensitivity to verapamil; cardiogenic shock; second or third degree atrioventricular block; sick sinus syndrome; severe heart failure
Precautions and warnings
monitor hepatic function in patients with liver impairment; monitor electrocardiogram in patients with conduction disturbances
Serious side effects
anaphylaxis — requires immediate medical attention; heart block — requires immediate medical attention
Patient summary
Utilized to manage hypertension, formulated to target calcium channels and support stable blood pressure control.
Mechanism of action
Verampil inhibits the transmembrane influx of calcium ions into cardiac muscle and vascular smooth muscle cells. This relaxation of vascular smooth muscle dilates arterioles, decreasing peripheral vascular resistance and reducing blood pressure, whilst also slowing conduction through the atrioventricular node.
Pregnancy and breastfeeding
Pregnancy: Use only if clearly indicated and no safer alternative exists. Breastfeeding: Excreted in breast milk; advise use with caution.
Verampil
Utilized to manage hypertension, formulated to target calcium channels and support stable blood pressure control.
Editorial Notes
- Active ingredient(s): Verapamil
- Listed indication(s): Hypertension, Angina Pectoris, Supraventricular Arrhythmias