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Medicine details

Conditions: Major Depressive Disorder
Generalized Anxiety Disorder
Alternative names: Efexor; Venlafaxine XL
Therapeutic class: Serotonin-Norepinephrine Reuptake Inhibitor (SNRI)
Pharmacological class: SNRI
Known off-label uses: social anxiety disorder
Contraindications: concurrent use of MAO inhibitors; uncontrolled angle-closure glaucoma
Minor side effects: nausea; dry mouth; headache; dizziness; insomnia
Moderate side effects: sweating; fatigue; decreased appetite; constipation
Dosage forms: Tablet
Administration route: Oral use
Prescription status: POM
Manufacturer: Sun Pharma
Onset Time: 2–4 weeks
Duration: indefinite
Storage instructions: Store in a cool, dry place.
Drug interactions: MAO inhibitors; triptans; St. John's Wort
Age restrictions: Not recommended for children under 18.

Precautions and warnings

do not stop treatment abruptly; monitor blood pressure periodically; risk of cognitive impairment

Serious side effects

serotonin syndrome — requires immediate medical attention; suicidal ideation — requires immediate medical attention

Patient summary

utilized to target depressive symptoms and to support treatment against anxiety disorders.

Mechanism of action

Acts by inhibiting the reuptake of serotonin and noradrenaline in the brain, which enhances neurotransmission and helps to alleviate mood disorders.

Pregnancy and breastfeeding

Pregnancy: Use only if clearly necessary. Breastfeeding: Clinical decision required as it is excreted in human milk.

utilized to target depressive symptoms and to support treatment against anxiety disorders.