Varenicline Tablets
Developed to target nicotine addiction pathways, utilized to support patients to mitigate withdrawal symptoms and cravings while quitting smoking.
Strengths: 0.5 · 1mg
Where to Check Availability
Medicine details
- Conditions
- Alternative names
Champix
- Therapeutic class
smoking cessation aid
- Pharmacological class
nicotinic receptor partial agonist
- Contraindications
hypersensitivity to varenicline
- Precautions and warnings
monitor for changes in behaviour or mood; may impair ability to drive
- Minor side effects
nausea; headache; insomnia
- Moderate side effects
vivid dreams; abdominal pain
- Dosage forms
Film-coated tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Pfizer
- Onset Time
1–2 weeks
- Duration
24 hours
- Storage instructions
Store below 30°C.
- Drug interactions
nicotine replacement therapy
- Age restrictions
Adults only.
- Pregnancy and breastfeeding
Pregnancy: not recommended. Breastfeeding: not recommended.
Serious side effects
suicidal ideation — requires immediate medical attention; severe allergic reaction — requires immediate medical attention
Patient summary
Developed to target nicotine addiction pathways, utilized to support patients to mitigate withdrawal symptoms and cravings while quitting smoking.
Mechanism of action
Varenicline acts as a partial agonist at alpha-4-beta-2 nicotinic acetylcholine receptors in the brain. It provides enough receptor stimulation to reduce nicotine withdrawal and craving while simultaneously blocking nicotine from binding to these receptors, making smoking less rewarding.
Varenicline Tablets
Developed to target nicotine addiction pathways, utilized to support patients to mitigate withdrawal symptoms and cravings while quitting smoking.
Editorial Notes
- Active ingredient(s): Varenicline
- Listed indication(s): Tobacco Dependence
Usually available as
- 60 tablets - 0.5 mg1157-0-5-mg-13676
- 30 tablets - 1 mg1157-1-mg-13672