Wellbutrin Sr
Indicated to address nicotine dependence, intended to mitigate withdrawal symptoms and support cessation efforts.
Strengths: 150mg
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Medicine details
- Alternative names
Zyban
- Therapeutic class
Smoking Cessation Aid; Antidepressant
- Pharmacological class
Aminoketone
- Minor side effects
dry mouth; insomnia; headache; nausea
- Moderate side effects
tremor; anxiety; dizziness
- Dosage forms
Modified-release tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
GSK
- Onset Time
1–2 weeks
- Duration
7–12 weeks
- Storage instructions
Store below 25°C in original packaging.
- Drug interactions
alcohol; MAO inhibitors; levodopa
- Age restrictions
Not for use in individuals under 18 years.
Contraindications
hypersensitivity to bupropion; seizure disorder; bulimia or anorexia nervosa; severe hepatic cirrhosis; current or prior use of monoamine oxidase inhibitors
Precautions and warnings
risk of seizure is dose-dependent; avoid abrupt discontinuation; monitor for neuropsychiatric symptoms
Serious side effects
seizure — requires immediate medical attention; angioedema — requires immediate medical attention
Patient summary
Indicated to address nicotine dependence, intended to mitigate withdrawal symptoms and support cessation efforts.
Mechanism of action
Bupropion is a relatively weak inhibitor of the neuronal uptake of serotonin and norepinephrine and inhibits the neuronal uptake of dopamine. Its mechanism in smoking cessation is not fully elucidated but involves noradrenergic and dopaminergic pathways.
Pregnancy and breastfeeding
Pregnancy: Use with caution only if benefit outweighs risk. Breastfeeding: Not recommended due to excretion in breast milk.
Wellbutrin Sr
Indicated to address nicotine dependence, intended to mitigate withdrawal symptoms and support cessation efforts.
Editorial Notes
- Active ingredient(s): Bupropion
- Listed indication(s): Tobacco Dependence, Major Depressive Disorder
Available option
- 90 tablets - 150 mg104-150-mg-1615