Champix
Designed to manage nicotine addiction and indicated to support smoking cessation by mitigating cravings and relieving withdrawal discomfort during treatment.
Strengths: 0.5 · 1mg
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Medicine details
- Conditions
- Therapeutic class
Smoking Cessation Aid
- Pharmacological class
Nicotinic Receptor Partial Agonist
- Contraindications
hypersensitivity to varenicline
- Precautions and warnings
monitor for neuropsychiatric symptoms; caution with alcohol intake
- Minor side effects
nausea; insomnia
- Moderate side effects
vivid dreams; headache
- Dosage forms
Film-coated tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Pfizer
- Onset Time
1–2 weeks
- Duration
12 weeks
- Storage instructions
Store below 30°C.
- Drug interactions
nicotine replacement therapy
- Age restrictions
18 years and older.
- Pregnancy and breastfeeding
Not recommended during pregnancy.
Serious side effects
suicidal ideation — requires immediate medical attention; depression — requires immediate medical attention
Patient summary
Designed to manage nicotine addiction and indicated to support smoking cessation by mitigating cravings and relieving withdrawal discomfort during treatment.
Mechanism of action
Varenicline acts as a partial agonist at alpha-4-beta-2 nicotinic acetylcholine receptors. It stimulates these receptors to relieve nicotine withdrawal cravings while simultaneously blocking nicotine from binding to them, which reduces the reinforcing effects of smoking.
Champix
Designed to manage nicotine addiction and indicated to support smoking cessation by mitigating cravings and relieving withdrawal discomfort during treatment.
Editorial Notes
- Active ingredient(s): Varenicline
- Listed indication(s): Smoking Cessation
Usually available as
- 60 tablets - 0.5 mg996-0-5-mg-12588
- 30 tablets - 1 mg996-1-mg-12579