Rabeprazole Tablets

Developed to manage gastro-oesophageal reflux disease and to alleviate acid-related symptoms by reducing the amount of acid produced in the stomach.

Strengths: 10 · 20mg

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Medicine details

Conditions
Alternative names

Pariet

Therapeutic class

Proton Pump Inhibitor

Pharmacological class

Proton Pump Inhibitor

Known off-label uses

eradicating helicobacter pylori

Contraindications

hypersensitivity to rabeprazole

Minor side effects

headache; nausea; abdominal pain; diarrhoea

Moderate side effects

constipation; flatulence; dry mouth; insomnia

Dosage forms

Gastro-resistant tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Eisai

Onset Time

1–2 hours

Duration

24 hours

Storage instructions

Store at room temperature in a dry place.

Drug interactions

methotrexate; warfarin; ketoconazole

Age restrictions

Adults 18 years and older.

Pregnancy and breastfeeding

Pregnancy: Avoid unless essential. Breastfeeding: Not recommended.

Precautions and warnings

long-term therapy may impact magnesium levels; use caution for patients with liver impairment; may mask symptoms of gastric malignancy

Serious side effects

interstitial nephritis — requires immediate medical attention; serious skin reactions — requires immediate medical attention; agranulocytosis — requires immediate medical attention

Patient summary

Developed to manage gastro-oesophageal reflux disease and to alleviate acid-related symptoms by reducing the amount of acid produced in the stomach.

Mechanism of action

Rabeprazole is a proton pump inhibitor. It blocks the final stage of gastric acid secretion by inhibiting the H+/K+-ATPase enzyme system at the secretory surface of the gastric parietal cells.

Rabeprazole Tablets

Developed to manage gastro-oesophageal reflux disease and to alleviate acid-related symptoms by reducing the amount of acid produced in the stomach.

Editorial Notes

  • Active ingredient(s): Rabeprazole
  • Listed indication(s): Gastro-oesophageal Reflux Disease, Peptic Ulcer Disease

Usually available as

  • 360 tablets - 10 mg1136-10-mg-13480
  • 180 tablets - 20 mg1136-20-mg-13485