Quetiapine Tablets

formulated to manage schizophrenia and bipolar disorder to mitigate acute symptoms and stabilize mood.

Strengths: 25 · 50 · 100 · 200 · 300mg

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Medicine details

Conditions
Alternative names

Seroquel; Seroquel XL

Therapeutic class

Atypical Antipsychotic

Pharmacological class

Dibenzo-thiazepine derivative

Known off-label uses

insomnia

Contraindications

hypersensitivity to quetiapine; concurrent use of cytochrome P450 3A4 inhibitors

Minor side effects

dizziness; dry mouth; somnolence; headache; increased weight

Moderate side effects

tachycardia; constipation; dyspepsia; asthenia

Dosage forms

Film-coated tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

AstraZeneca

Onset Time

1–2 weeks

Duration

long-term

Storage instructions

Store below 30°C.

Drug interactions

alcohol; cytochrome P450 inhibitors; antihypertensives

Age restrictions

Not recommended for children and adolescents under 18 years.

Precautions and warnings

may affect blood sugar control; monitor for suicidal ideation; use with caution in elderly patients with dementia

Serious side effects

neuroleptic malignant syndrome — requires immediate medical attention; tardive dyskinesia — requires immediate medical attention; neutropenia — requires immediate medical attention

Patient summary

formulated to manage schizophrenia and bipolar disorder to mitigate acute symptoms and stabilize mood.

Mechanism of action

Quetiapine acts as an antagonist at several neurotransmitter receptors, including serotonin (5HT2) and dopamine (D2) receptors. By modulating these pathways in the brain, it helps reduce the intensity of psychotic symptoms and stabilize moods in patients with psychiatric disorders.

Pregnancy and breastfeeding

Pregnancy: Use only if the benefit justifies the risk. Breastfeeding: Discontinue breastfeeding during treatment.

Quetiapine Tablets

formulated to manage schizophrenia and bipolar disorder to mitigate acute symptoms and stabilize mood.

Editorial Notes

  • Active ingredient(s): Quetiapine
  • Listed indication(s): Schizophrenia, Bipolar Disorder, Major Depressive Disorder

Usually available as

  • 180 tablets - 25 mg1201-25-mg-14240
  • 90 tablets - 50 mg1201-50-mg-14230
  • 90 tablets - 100 mg1201-100-mg-14248