Zyprexa
indicated to manage schizophrenia and bipolar disorder and to support long-term symptom stability regarding mood regulation.
Strengths: 2.5 · 5 · 7.5 · 10 · 15 · 20mg
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Medicine details
- Conditions
- Therapeutic class
Second-Generation Antipsychotic
- Pharmacological class
Thienobenzodiazepine
- Contraindications
narrow-angle glaucoma; hypersensitivity to olanzapine
- Precautions and warnings
monitor blood sugar levels; watch for weight gain; avoid sudden discontinuation
- Minor side effects
somnolence; weight gain; dizziness
- Moderate side effects
orthostatic hypotension; elevated prolactin levels; dry mouth
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Eli Lilly
- Onset Time
1–2 weeks
- Duration
Daily
- Storage instructions
Store at room temperature in original container.
- Drug interactions
diazepam; alcohol; levodopa
- Age restrictions
Not recommended for children under 13.
Serious side effects
neuroleptic malignant syndrome — requires immediate medical attention; hyperglycaemia — requires immediate medical attention; tardive dyskinesia — requires immediate medical attention
Patient summary
indicated to manage schizophrenia and bipolar disorder and to support long-term symptom stability regarding mood regulation.
Mechanism of action
Olanzapine acts as an antagonist at both serotonin (5HT2A/2C) and dopamine (D2) receptors. It also exerts effects on muscarinic, histaminic, and adrenergic receptors to stabilize chemical signalling in the brain.
Pregnancy and breastfeeding
Use only if benefit outweighs risk. Breastfeeding: Use with caution; consult a doctor.
Zyprexa
indicated to manage schizophrenia and bipolar disorder and to support long-term symptom stability regarding mood regulation.
Editorial Notes
- Active ingredient(s): Olanzapine
- Listed indication(s): Schizophrenia, Bipolar Disorder
Usually available as
- 360 tablets - 2.5 mg294-2-5-mg-4690
- 180 tablets - 5 mg294-5-mg-4695
- 90 tablets - 7.5 mg294-7-5-mg-4699