Questran
Indicated for hypercholesterolaemia, utilized to target bile acids in the gut to alleviate elevated blood cholesterol and support lipid management.
Strengths: 4g
Where to Check Availability
Medicine details
- Conditions
- Therapeutic class
Bile Acid Sequestrant
- Pharmacological class
Ion Exchange Resin
- Contraindications
complete biliary obstruction
- Minor side effects
constipation; nausea
- Moderate side effects
abdominal bloating; flatulence; fat malabsorption
- Serious side effects
intestinal obstruction — requires immediate medical attention
- Dosage forms
Powder for oral suspension
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Bristol-Myers Squibb
- Onset Time
1–2 weeks
- Duration
24 hours
- Storage instructions
Store in a tightly closed container at room temperature.
- Drug interactions
warfarin; fat-soluble vitamins; thiazide diuretics
- Age restrictions
Use with caution in children.
- Pregnancy and breastfeeding
Pregnancy: Use only if necessary. Breastfeeding: Generally considered safe.
Precautions and warnings
take other medications at least one hour before or four hours after; maintain adequate fluid intake
Patient summary
Indicated for hypercholesterolaemia, utilized to target bile acids in the gut to alleviate elevated blood cholesterol and support lipid management.
Mechanism of action
Cholestyramine is a bile acid sequestrant. It binds to bile acids in the intestine, forming an insoluble complex that is excreted in faeces. This forces the liver to use cholesterol to produce more bile acids, lowering overall blood cholesterol levels.
Questran
Indicated for hypercholesterolaemia, utilized to target bile acids in the gut to alleviate elevated blood cholesterol and support lipid management.
Editorial Notes
- Active ingredient(s): Cholestyramine
- Listed indication(s): Hypercholesterolaemia, Pruritus
Available option
- 10 sachets - 4 g1538-4-g-18150