Orlistat Tablets

Developed to target weight management, indicated to support dietary efforts to reduce body weight by inhibiting the digestion of dietary fats.

Strengths: 60 · 120mg

Medicine details

Alternative names

Xenical; Alli

Therapeutic class

Anti-obesity Preparation

Pharmacological class

Lipase Inhibitor

Contraindications

chronic malabsorption syndrome; cholestasis; pregnancy

Minor side effects

flatulence; faecal urgency; steatorrhoea

Moderate side effects

abdominal pain; faecal incontinence

Dosage forms

Tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Roche

Onset Time

1–2 days

Duration

3–4 hours

Storage instructions

Store below 25°C, away from moisture and direct heat.

Drug interactions

warfarin; levothyroxine; ciclosporin

Age restrictions

Recommended for adults only.

Precautions and warnings

maintain a low-fat diet; may reduce absorption of fat-soluble vitamins; use with a vitamin supplement

Serious side effects

liver injury — requires immediate medical attention; oxalate nephropathy — requires immediate medical attention

Patient summary

Developed to target weight management, indicated to support dietary efforts to reduce body weight by inhibiting the digestion of dietary fats.

Mechanism of action

Orlistat acts as a specific inhibitor of gastrointestinal lipases, reducing the absorption of a proportion of dietary fat consumed in a meal.

Pregnancy and breastfeeding

Pregnancy: Not recommended. Breastfeeding: Not recommended due to potential excretion in milk.

Orlistat Tablets

Developed to target weight management, indicated to support dietary efforts to reduce body weight by inhibiting the digestion of dietary fats.

Editorial Notes

  • Active ingredient(s): Orlistat
  • Listed indication(s): Obesity, Overweight

Usually available as

  • 90 tablets - 60 mg562-60-mg-1630
  • 90 tablets - 120 mg562-120-mg-1624