Rybelsus

Indicated to manage type 2 diabetes and developed to support blood sugar control and alleviate weight-related health risks in patients.

Strengths: 3 · 7 · 14mg

Medicine details

Alternative names

Ozempic; Wegovy

Therapeutic class

Glucagon-like Peptide-1 (GLP-1) Receptor Agonist

Pharmacological class

GLP-1 Receptor Agonist

Known off-label uses

obesity

Precautions and warnings

maintain adequate hydration; monitor blood sugar levels

Minor side effects

nausea; diarrhoea

Moderate side effects

vomiting; abdominal pain; constipation

Dosage forms

Tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Novo Nordisk

Onset Time

weeks

Duration

long term

Storage instructions

Store in original card in a dry place.

Drug interactions

insulin; sulphonylureas

Age restrictions

18 years and older.

Pregnancy and breastfeeding

Not recommended during pregnancy.

Contraindications

medullary thyroid carcinoma history; multiple endocrine neoplasia syndrome type 2

Serious side effects

pancreatitis — requires immediate medical attention; gallbladder disease — requires immediate medical attention

Patient summary

Indicated to manage type 2 diabetes and developed to support blood sugar control and alleviate weight-related health risks in patients.

Mechanism of action

Semaglutide is a GLP-1 receptor agonist that mimics the body's natural incretin hormone. It enhances insulin secretion, suppresses glucagon levels, and slows gastric emptying, which helps to lower blood glucose concentrations and promote satiety.

Rybelsus

Indicated to manage type 2 diabetes and developed to support blood sugar control and alleviate weight-related health risks in patients.

Editorial Notes

  • Active ingredient(s): Semaglutide
  • Listed indication(s): Type 2 Diabetes Mellitus

Usually available as

  • 10 tablets - 3 mg998-3-mg-12607
  • 10 tablets - 7 mg998-7-mg-12608
  • 10 tablets - 14 mg998-14-mg-12609