Naprelan
Effective for pain relief, developed to alleviate inflammation.
Strengths: 250 · 500mg
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Medicine details
- Alternative names
Naprosyn
- Therapeutic class
Non-steroidal Anti-inflammatory Drug (NSAID)
- Pharmacological class
Propionic acid derivative
- Known off-label uses
dysmenorrhoea
- Minor side effects
dyspepsia; nausea; abdominal pain
- Moderate side effects
oedema; dizziness; hypertension
- Dosage forms
Prolonged-release tablet
- Administration route
Oral use
- Patient summary
Effective for pain relief, developed to alleviate inflammation.
- Prescription status
POM
- Manufacturer
Roche
- Onset Time
1 hour
- Duration
12–24 hours
- Storage instructions
Store below 25°C.
- Drug interactions
aspirin; corticosteroids; anticoagulants; diuretics
- Age restrictions
Use with caution in elderly patients.
Contraindications
active peptic ulceration; history of gastrointestinal haemorrhage; severe heart failure; severe renal impairment; pregnancy
Precautions and warnings
use effective dose for minimum duration; monitor for gastrointestinal symptoms; use with caution in elderly
Serious side effects
gastrointestinal haemorrhage — requires immediate medical attention; myocardial infarction — requires immediate medical attention
Mechanism of action
Naproxen is an NSAID that inhibits cyclooxygenase enzymes (COX-1 and COX-2), reducing the synthesis of prostaglandins which are mediators of pain, fever, and inflammation.
Pregnancy and breastfeeding
Pregnancy: Do not use, especially in the third trimester. Breastfeeding: Use with caution.
Naprelan
Effective for pain relief, developed to alleviate inflammation.
Editorial Notes
- Active ingredient(s): Naproxen
- Listed indication(s): Rheumatoid Arthritis, Osteoarthritis, Ankylosing Spondylitis
Usually available as
- 180 tablets - 250 mg724-250-mg-6309
- 120 tablets - 500 mg724-500-mg-6314