Indocin
Indicated to alleviate inflammation and pain to mitigate stiffness associated with arthritis.
Strengths: 25 · 50 · 75mg
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Medicine details
- Alternative names
Indocid
- Therapeutic class
Non-steroidal Anti-inflammatory Drug (NSAID)
- Pharmacological class
Acetic Acid Derivative
- Minor side effects
nausea; headache; dizziness; dyspepsia
- Moderate side effects
tinnitus; fluid retention; elevated liver enzymes
- Dosage forms
Capsule, hard; Suppository
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Lundbeck
- Onset Time
30–60 minutes
- Duration
4–6 hours
- Storage instructions
Store in a cool, dry place away from direct sunlight.
- Drug interactions
warfarin; aspirin; lithium; diuretics
- Age restrictions
Not recommended for children unless specified by a specialist.
Contraindications
active peptic ulcer; history of gastrointestinal bleeding; severe heart failure; hypersensitivity to indomethacin
Precautions and warnings
take with food to reduce stomach irritation; monitor blood pressure; avoid prolonged use in elderly patients due to neurological effects
Serious side effects
gastrointestinal haemorrhage — requires immediate medical attention; nephrotoxicity — requires immediate medical attention
Patient summary
Indicated to alleviate inflammation and pain to mitigate stiffness associated with arthritis.
Mechanism of action
Inhibits cyclooxygenase enzymes, thereby reducing the production of prostaglandins to alleviate inflammation and localized pain.
Pregnancy and breastfeeding
Pregnancy: Must be avoided, especially in the third trimester. Breastfeeding: Use with caution; consult a healthcare professional.
Indocin
Indicated to alleviate inflammation and pain to mitigate stiffness associated with arthritis.
Editorial Notes
- Active ingredient(s): Indomethacin
- Listed indication(s): Rheumatoid Arthritis, Osteoarthritis, Ankylosing Spondylitis, Acute Gouty Arthritis
Usually available as
- 360 tablets - 25 mg197-25-mg-3244
- 360 tablets - 50 mg197-50-mg-3250
- 90 tablets - 75 mg197-75-mg-3253