Celebrex

Indicated for joint inflammation, this treatment is formulated to target pain and designed to mitigate symptoms effectively for better mobility.

Strengths: 100 · 200mg

Medicine details

Therapeutic class

Non-steroidal Anti-inflammatory Drug (NSAID)

Pharmacological class

COX-2 Inhibitor

Contraindications

active peptic ulcer; severe hepatic impairment; ischaemic heart disease

Minor side effects

dyspepsia; diarrhoea; abdominal pain

Moderate side effects

peripheral oedema; hypertension; insomnia

Dosage forms

Capsule, hard

Administration route

Oral use

Prescription status

POM

Manufacturer

Pfizer

Onset Time

1–2 hours

Duration

12–24 hours

Storage instructions

Store at room temperature below 30°C.

Drug interactions

fluconazole; warfarin; lithium

Age restrictions

Monitor elderly patients for renal and cardiovascular health.

Pregnancy and breastfeeding

Do not use during the third trimester of pregnancy.

Precautions and warnings

may increase risk of cardiovascular events; use with caution in patients with hypertension

Serious side effects

myocardial infarction — requires immediate medical attention; gastrointestinal haemorrhage — requires immediate medical attention

Patient summary

Indicated for joint inflammation, this treatment is formulated to target pain and designed to mitigate symptoms effectively for better mobility.

Mechanism of action

This medication belongs to the cox-2 inhibitor class. It functions by selectively blocking the cyclooxygenase-2 enzyme, which reduces the production of prostaglandins that cause inflammation and pain, while sparing most of the protective stomach-lining enzymes.

Celebrex

Indicated for joint inflammation, this treatment is formulated to target pain and designed to mitigate symptoms effectively for better mobility.

Editorial Notes

  • Active ingredient(s): Celecoxib
  • Listed indication(s): Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis

Usually available as

  • 180 tablets - 100 mg175-100-mg-4820
  • 90 tablets - 200 mg175-200-mg-4825