Medroxyprogesterone Tablets
Formulated to alleviate hormonal imbalances, indicated to support the management of menstrual disorders and severe uterine conditions.
Strengths: 5 · 10mg
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Medicine details
- Alternative names
Provera
- Therapeutic class
progestogen
- Pharmacological class
progestogen
- Known off-label uses
hormone replacement therapy adjunct
- Contraindications
undiagnosed vaginal bleeding; severe hepatic impairment; known pregnancy
- Precautions and warnings
monitor for signs of venous thromboembolism; regular screening recommended
- Minor side effects
nausea; headache; fatigue
- Moderate side effects
weight increase; irregular uterine bleeding; depression
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Pfizer
- Onset Time
Several days
- Duration
Long-acting
- Storage instructions
Store below 25°C.
- Drug interactions
rifampicin; phenytoin
- Age restrictions
Adults only.
- Pregnancy and breastfeeding
Pregnancy: contra-indicated. Breastfeeding: generally compatible.
Serious side effects
deep vein thrombosis — requires immediate medical attention; pulmonary embolism — requires immediate medical attention
Patient summary
Formulated to alleviate hormonal imbalances, indicated to support the management of menstrual disorders and severe uterine conditions.
Mechanism of action
Medroxyprogesterone is a synthetic progestogen. It creates a transformation in the endometrium from a proliferative to a secretory state. It inhibits the secretion of pituitary gonadotropins, which prevents follicular maturation and ovulation.
Medroxyprogesterone Tablets
Formulated to alleviate hormonal imbalances, indicated to support the management of menstrual disorders and severe uterine conditions.
Editorial Notes
- Active ingredient(s): Medroxyprogesterone
- Listed indication(s): Endometriosis, Secondary Amenorrhea, Abnormal Uterine Bleeding
Usually available as
- 180 tablets - 5 mg1161-5-mg-17402
- 120 tablets - 10 mg1161-10-mg-13727