Cycrin

This medicine is utilized to manage hormonal conditions like endometriosis and is indicated to support the regulation of the menstrual cycle in women.

Strengths: 5 · 10mg

Medicine details

Alternative names

Provera

Therapeutic class

Progestogen

Pharmacological class

Progesterone

Minor side effects

headache; nausea; dizziness

Moderate side effects

weight gain; breast tenderness; insomnia

Dosage forms

Tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Pfizer

Onset Time

1–3 hours

Duration

24 hours

Storage instructions

Store at room temperature, away from moisture and direct light.

Drug interactions

aminoglutethimide

Age restrictions

Not recommended for paediatric patients.

Contraindications

hypersensitivity to medroxyprogesterone; undiagnosed vaginal bleeding; severe hepatic impairment; pregnancy

Precautions and warnings

risk of venous thromboembolism; use with caution in patients with history of depression; may cause irregular bleeding patterns; monitor hepatic function

Serious side effects

anaphylaxis — requires immediate medical attention; venous thromboembolism — requires immediate medical attention

Patient summary

This medicine is utilized to manage hormonal conditions like endometriosis and is indicated to support the regulation of the menstrual cycle in women.

Mechanism of action

Medroxyprogesterone is a synthetic progestogen that acts on the endometrium, transforming proliferative endometrium into secretory endometrium. It effectively inhibits the production of pituitary gonadotropins, which prevents follicular maturation and ovulation, thereby supporting management of specific reproductive healthcare needs.

Pregnancy and breastfeeding

Pregnancy: Do not use during pregnancy. Breastfeeding: Use with caution as it may be excreted in breast milk.

Cycrin

This medicine is utilized to manage hormonal conditions like endometriosis and is indicated to support the regulation of the menstrual cycle in women.

Editorial Notes

  • Active ingredient(s): Medroxyprogesterone
  • Listed indication(s): Secondary Amenorrhea, Endometriosis, Dysfunctional Uterine Bleeding

Usually available as

  • 180 tablets - 5 mg630-5-mg-2616
  • 90 tablets - 10 mg630-10-mg-2620