Lodine
indicated to alleviate pain and inflammation in chronic musculoskeletal conditions to support mobility.
Strengths: 200 · 300 · 400mg
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Medicine details
- Conditions
- Alternative names
Etopan
- Therapeutic class
Non-steroidal anti-inflammatory drug (NSAID)
- Pharmacological class
Pyranoindole acetic acid
- Known off-label uses
ankylosing spondylitis
- Minor side effects
nausea; dyspepsia; dizziness; headache
- Moderate side effects
fluid retention; abdominal pain; constipation; flatulence
- Dosage forms
Tablet; Capsule, hard
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Wyeth
- Onset Time
30–60 minutes
- Duration
4–8 hours
- Storage instructions
Store below 25°C in a dry place.
- Drug interactions
warfarin; lithium; alcohol
- Age restrictions
Not for use in children.
Contraindications
hypersensitivity to etodolac; active peptic ulceration; history of asthma triggered by aspirin; severe heart failure
Precautions and warnings
use with caution in elderly patients; monitor blood pressure regularly; risk of gastrointestinal bleeding
Serious side effects
gastrointestinal haemorrhage — requires immediate medical attention; myocardial infarction — requires immediate medical attention
Patient summary
indicated to alleviate pain and inflammation in chronic musculoskeletal conditions to support mobility.
Mechanism of action
Etodolac works by inhibiting the enzymes cyclooxygenase-1 and cyclooxygenase-2, which are responsible for the synthesis of prostaglandins that mediate pain and inflammation.
Pregnancy and breastfeeding
Pregnancy: Avoid, particularly in the third trimester. Breastfeeding: Not recommended.
Lodine
indicated to alleviate pain and inflammation in chronic musculoskeletal conditions to support mobility.
Editorial Notes
- Active ingredient(s): Etodolac
- Listed indication(s): Osteoarthritis, Rheumatoid Arthritis
Available option
- 60 tablets - 400 mg1556-400-mg-18076