Gutron

developed to support blood pressure regulation to address orthostatic hypotension.

Strengths: 5mg

Medicine details

Alternative names

Bramox

Therapeutic class

Alpha-adrenergic agonist

Pharmacological class

Sympathomimetic agent

Contraindications

severe heart disease; pheochromocytoma; severe renal impairment; hyperthyroidism

Precautions and warnings

monitor blood pressure in the supine position; avoid use before bedtime

Minor side effects

piloerection; pruritus; scalp tingling

Moderate side effects

urinary retention; supine hypertension

Dosage forms

Tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Takeda

Onset Time

30–60 minutes

Duration

2–4 hours

Storage instructions

Store below 25°C, away from light.

Drug interactions

alpha-blockers; antihypertensives

Age restrictions

Not recommended for children.

Pregnancy and breastfeeding

Pregnancy: Consult a specialist usage only. Breastfeeding: Use with caution.

Serious side effects

hypertensive crisis — requires immediate medical attention; bradycardia — requires immediate medical attention

Patient summary

developed to support blood pressure regulation to address orthostatic hypotension.

Mechanism of action

Midodrine is a prodrug that acts as a selective alpha-1 adrenergic agonist, causing vasoconstriction of arterioles and veins, thereby increasing blood pressure.

Gutron

developed to support blood pressure regulation to address orthostatic hypotension.

Editorial Notes

  • Active ingredient(s): Midodrine
  • Listed indication(s): Orthostatic Hypotension