Esidrix
indicated to manage fluid retention through increased sodium and water excretion in the kidneys.
Strengths: 12.5 · 25mg
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Medicine details
- Conditions
- Alternative names
Hydrosaluric
- Therapeutic class
Thiazide Diuretic
- Pharmacological class
Thiazide
- Minor side effects
dizziness; fatigue; electrolyte imbalance
- Moderate side effects
hypotension; hyperuricaemia; photosensitivity
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Novartis
- Onset Time
1–2 hours
- Duration
6–12 hours
- Storage instructions
Store at room temperature in a dry place.
- Drug interactions
alcohol; lithium; corticosteroids
- Age restrictions
Safety in children not fully established.
Contraindications
hypersensitivity to thiazides; anuria; severe renal impairment; addison's disease
Precautions and warnings
monitor electrolyte levels regularly; may cause dehydration; report any signs of skin lesion clusters
Serious side effects
pancreatitis — requires immediate medical attention; acute renal failure — requires immediate medical attention
Patient summary
indicated to manage fluid retention through increased sodium and water excretion in the kidneys.
Mechanism of action
Esidrix works by inhibiting the reabsorption of sodium and chloride in the distal convoluted tubules of the kidney. This increases the excretion of sodium, water, and potassium, which reduces total blood volume and thereby lowers blood pressure and relieves oedema associated with congestive heart failure.
Pregnancy and breastfeeding
Pregnancy: Not recommended due to potential neonatal side effects. Breastfeeding: Avoid as it may suppress lactation.
Esidrix
indicated to manage fluid retention through increased sodium and water excretion in the kidneys.
Editorial Notes
- Active ingredient(s): Hydrochlorothiazide
- Listed indication(s): Hypertension, Oedema
Usually available as
- 180 tablets - 12.5 mg664-12-5-mg-2878
- 90 tablets - 25 mg664-25-mg-2882