Frumil
utilized to alleviate fluid retention, balancing potassium levels by combining a potassium-sparing agent with a loop diuretic.
Strengths: 40/5mg
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Medicine details
- Conditions
- Therapeutic class
Diuretic combo
- Pharmacological class
Potassium-sparing diuretic; Loop diuretic
- Contraindications
hyperkalaemia; anuria; severe renal impairment; addison's disease
- Minor side effects
headache; nausea; polyuria
- Moderate side effects
dizziness; muscle cramps; hypotension
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Sanofi
- Onset Time
1 hour
- Duration
6–8 hours
- Storage instructions
Store below 25°C.
- Drug interactions
potassium supplements; ace inhibitors; lithium
- Age restrictions
Use with caution in elderly.
- Pregnancy and breastfeeding
Avoid during pregnancy unless necessary. Use with caution during breastfeeding.
Precautions and warnings
monitor serum electrolytes; risk of dehydration; caution in prostatic hypertrophy
Serious side effects
severe hyperkalaemia — requires immediate medical attention; anaphylaxis — requires immediate medical attention
Patient summary
utilized to alleviate fluid retention, balancing potassium levels by combining a potassium-sparing agent with a loop diuretic.
Mechanism of action
Furosemide inhibits sodium and chloride reabsorption in the loop of Henle, while amiloride acts on the distal tubule to prevent potassium loss, balancing fluid output.
Frumil
utilized to alleviate fluid retention, balancing potassium levels by combining a potassium-sparing agent with a loop diuretic.
Editorial Notes
- Active ingredient(s): Amiloride, Furosemide
- Listed indication(s): Oedema, Hypertension