Eplerenone Tablets
designed to mitigate hypertension symptoms indicated to support cardiovascular health.
Strengths: 25 · 50mg
Where to Check Availability
Medicine details
- Conditions
- Alternative names
Inspra
- Therapeutic class
Aldosterone Antagonist
- Pharmacological class
Potassium-Sparing Diuretic
- Contraindications
hyperkalaemia; severe renal impairment; concurrent use of potassium supplements
- Minor side effects
dizziness; hyperkalaemia
- Moderate side effects
diarrhoea; cough; fatigue
- Dosage forms
Film-coated tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Upjohn
- Onset Time
2–4 weeks
- Duration
24 hours
- Storage instructions
Store below 30°C in a dry place.
- Drug interactions
potassium supplements; ACE inhibitors; potassium-sparing diuretics
- Age restrictions
Not for paediatric use.
- Pregnancy and breastfeeding
Not recommended during pregnancy.
Precautions and warnings
regular monitoring of serum potassium levels required; use with caution in moderate renal impairment
Serious side effects
severe hyperkalaemia — requires immediate medical attention; angioedema — requires immediate medical attention
Patient summary
designed to mitigate hypertension symptoms indicated to support cardiovascular health.
Mechanism of action
Eplerenone competes with aldosterone for mineralocorticoid receptors, reducing sodium reabsorption and preventing myocardial fibrosis and ventricular hypertrophy, thereby lowering blood pressure and pressure on the heart.
Eplerenone Tablets
designed to mitigate hypertension symptoms indicated to support cardiovascular health.
Editorial Notes
- Active ingredient(s): Eplerenone
- Listed indication(s): Heart Failure, Hypertension
Usually available as
- 60 tablets - 25 mg1376-25-mg-16522
- 30 tablets - 50 mg1376-50-mg-16526