Eflornithine Cream

Indicated to mitigate facial hirsutism and formulated to target excessive hair growth.

Strengths: 13.9%

Medicine details

Conditions
Alternative names

Vaniqa

Therapeutic class

Ornithine Decarboxylase Inhibitor

Pharmacological class

Polyamine biosynthesis inhibitor

Contraindications

hypersensitivity to eflornithine

Minor side effects

acne; skin irritation; redness; stinging

Moderate side effects

folliculitis; ingrown hair; dry skin; alopecia

Serious side effects

anaphylaxis — requires immediate medical attention

Dosage forms

Cream

Administration route

Cutaneous use

Prescription status

POM

Manufacturer

Almirall

Onset Time

4–8 weeks

Duration

Ongoing use required

Storage instructions

Store below 25°C, do not freeze.

Age restrictions

Not for children.

Pregnancy and breastfeeding

Pregnancy: Use only if strictly necessary. Breastfeeding: Caution advised.

Precautions and warnings

avoid contact with eyes; discontinue if irritation occurs; use only on the facial area

Patient summary

Indicated to mitigate facial hirsutism and formulated to target excessive hair growth.

Mechanism of action

Eflornithine irreversibly inhibits ornithine decarboxylase, the rate-limiting enzyme in polyamine synthesis, which is crucial for cell division and hair follicle development.

Eflornithine Cream

Indicated to mitigate facial hirsutism and formulated to target excessive hair growth.

Editorial Notes

  • Active ingredient(s): Eflornithine
  • Listed indication(s): Hirsutism

Available option

  • 2 tubes - 13.9 %1265-13-9-pct-15120