Doxepin Tablets
utilized to manage symptoms of major depressive disorder and anxiety to alleviate mental distress.
Strengths: 10 · 25 · 75mg
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Medicine details
- Alternative names
Sinequan
- Therapeutic class
Tricyclic Antidepressant
- Pharmacological class
Tricyclic Antidepressant
- Known off-label uses
insomnia
- Precautions and warnings
may cause significant drowsiness; monitor heart rate and blood pressure
- Minor side effects
drowsiness; dry mouth; blurred vision; constipation
- Moderate side effects
urinary retention; tachycardia; orthostatic hypotension; weight gain
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Pfizer
- Onset Time
2–4 weeks
- Duration
indefinite
- Storage instructions
Store in a cool, dark place.
- Drug interactions
alcohol; MAO inhibitors; antihypertensives
- Age restrictions
Not recommended for children under 12 years.
Contraindications
hypersensitivity to tricyclic antidepressants; urinary retention; narrow-angle glaucoma; recent myocardial infarction
Serious side effects
cardiac arrhythmia — requires immediate medical attention; seizures — requires immediate medical attention
Patient summary
utilized to manage symptoms of major depressive disorder and anxiety to alleviate mental distress.
Mechanism of action
Doxepin inhibits the reuptake of norepinephrine and serotonin into nerve terminals. By increasing the levels of these neurotransmitters in the synaptic cleft, it improves mood regulation and relieves symptoms of anxiety.
Pregnancy and breastfeeding
Pregnancy: Potential harm; use only when strictly necessary. Breastfeeding: Not recommended.
Doxepin Tablets
utilized to manage symptoms of major depressive disorder and anxiety to alleviate mental distress.
Editorial Notes
- Active ingredient(s): Doxepin
- Listed indication(s): Major Depressive Disorder, Anxiety Disorder
Usually available as
- 360 tablets - 25 mg1205-25-mg-14292
- 180 tablets - 75 mg1205-75-mg-14297