Colchicine Tablets

Indicated to manage gout flares, developed to mitigate joint inflammation rapidly and provide effective relief from acute gouty attacks.

Strengths: 0.5mg

Medicine details

Conditions
Alternative names

Colcrys

Therapeutic class

Gout Suppressant

Pharmacological class

Alkaloid

Known off-label uses

familial mediterranean fever

Contraindications

severe renal impairment; severe hepatic impairment

Precautions and warnings

monitor for muscle pain

Minor side effects

nausea; diarrhoea; abdominal pain

Moderate side effects

vomiting

Serious side effects

myotoxicity — requires immediate medical attention

Dosage forms

Tablet

Administration route

Oral use

Prescription status

POM

Onset Time

12–24 hours

Duration

daily

Storage instructions

Store at room temperature, away from light.

Drug interactions

Grapefruit; Clarithromycin

Age restrictions

Not recommended for children.

Pregnancy and breastfeeding

Pregnancy: Not recommended. Breastfeeding: Not recommended.

Patient summary

Indicated to manage gout flares, developed to mitigate joint inflammation rapidly and provide effective relief from acute gouty attacks.

Mechanism of action

Colchicine inhibits microtubule polymerisation in neutrophils, effectively reducing the inflammatory response to urate crystals within the joint.

Colchicine Tablets

Indicated to manage gout flares, developed to mitigate joint inflammation rapidly and provide effective relief from acute gouty attacks.

Editorial Notes

  • Active ingredient(s): Colchicine
  • Listed indication(s): Gout

Available option

  • 120 tablets - 0.5 mg951-0-5-mg-11980