Clomipramine Tablets
The product is utilized to manage symptoms of obsessive-compulsive disorder or related clinical conditions.
Strengths: 10 · 25 · 50mg
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Medicine details
- Alternative names
Anafranil
- Therapeutic class
Tricyclic Antidepressant
- Pharmacological class
Tricyclic Antidepressant (TCA)
- Known off-label uses
chronic pain
- Minor side effects
nausea; dizziness; dry mouth; headache; constipation
- Moderate side effects
sweating; tremor; weight gain; sleep disturbance; blurred vision
- Dosage forms
Film-coated tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Alliance Pharmaceuticals
- Onset Time
2–4 weeks
- Duration
24 hours
- Storage instructions
Store below 25°C in a dry place.
- Drug interactions
alcohol; monoamine oxidase inhibitors; fluoxetine; cimetidine
- Age restrictions
Not recommended for children under 5 years.
Contraindications
hypersensitivity to clomipramine; recent myocardial infarction; cardiac arrhythmias; concurrent use of monoamine oxidase inhibitors; severe hepatic impairment
Precautions and warnings
may impair ability to drive or operate machinery; use with caution in patients with epilepsy; monitor for suicidal thoughts
Serious side effects
qt prolongation — requires immediate medical attention; seizures — requires immediate medical attention; serotonin syndrome — requires immediate medical attention
Patient summary
The product is utilized to manage symptoms of obsessive-compulsive disorder or related clinical conditions.
Mechanism of action
Clomipramine is a tricyclic antidepressant that acts by inhibiting the reuptake of both serotonin and noradrenaline at neuronal synapses, thereby increasing their availability in the central nervous system to help modulate mood and behavioral responses.
Pregnancy and breastfeeding
Pregnancy: Should be avoided unless clearly necessary. Breastfeeding: Small amounts pass into milk; clinical advice is required.
Clomipramine Tablets
The product is utilized to manage symptoms of obsessive-compulsive disorder or related clinical conditions.
Editorial Notes
- Active ingredient(s): Clomipramine
- Listed indication(s): Obsessive-compulsive Disorder, Phobic States, Cataplexy Associated with Narcolepsy
Usually available as
- 180 tablets - 10 mg1144-10-mg-13552
- 120 tablets - 25 mg1144-25-mg-13557
- 90 tablets - 50 mg1144-50-mg-13562