Bicalutamide Tablets
Developed to target prostate cancer activity, this medication is indicated to support the management of androgen-dependent disease progression in adult males.
Strengths: 50mg
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Medicine details
- Conditions
- Alternative names
Casodex
- Therapeutic class
Antiandrogen
- Pharmacological class
Non-steroidal antiandrogen
- Contraindications
hypersensitivity to bicalutamide; women; children
- Minor side effects
hot flushes; fatigue; constipation
- Moderate side effects
breast tenderness; gynaecomastia; nausea
- Dosage forms
Film-coated tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
AstraZeneca
- Onset Time
1–2 weeks
- Duration
long-term
- Storage instructions
Store in the original container at room temperature.
- Drug interactions
warfarin; ciclosporin
- Age restrictions
Not for use in children or adolescents.
- Pregnancy and breastfeeding
Not indicated for use in women.
Precautions and warnings
monitor liver function regularly; may cause dizziness; use with caution in hepatic impairment
Serious side effects
hepatic failure — requires immediate medical attention; interstitial lung disease — requires immediate medical attention
Patient summary
Developed to target prostate cancer activity, this medication is indicated to support the management of androgen-dependent disease progression in adult males.
Mechanism of action
Bicalutamide is a non-steroidal antiandrogen that inhibits the androgen receptor. By binding to these receptors, it prevents the action of androgens which stimulate the growth of prostate cancer cells, effectively mitigating tumour progression.
Bicalutamide Tablets
Developed to target prostate cancer activity, this medication is indicated to support the management of androgen-dependent disease progression in adult males.
Editorial Notes
- Active ingredient(s): Bicalutamide
- Listed indication(s): Prostate Cancer
Available option
- 30 tablets - 50 mg1351-50-mg-16269