Amantadine Tablets

Utilized to manage neurological symptoms, formulated to target movement disorders and to manage viral replication outcomes.

Strengths: 100mg

Neurology icon Neurology Amantadine icon Amantadine

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Medicine details

Conditions
Alternative names

Symmetrel

Therapeutic class

Antiparkinsonian

Pharmacological class

Adamantane derivative

Known off-label uses

drug-induced extrapyramidal symptoms; fatigue in multiple sclerosis

Contraindications

hypersensitivity to amantadine; history of gastric ulcer; history of convulsions

Minor side effects

nausea; dizziness; insomnia; dry mouth

Moderate side effects

peripheral oedema; confusion; hallucinations

Dosage forms

Tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Novartis

Onset Time

2–4 days

Duration

12–24 hours

Storage instructions

Store below 25°C, away from moisture.

Drug interactions

alcohol; anticholinergics

Age restrictions

Not recommended for children under 1 year.

Precautions and warnings

use with caution in elderly patients; may impair ability to drive or operate machinery; avoid sudden withdrawal of treatment

Serious side effects

heart failure — requires immediate medical attention; suicidal ideation — requires immediate medical attention

Patient summary

Utilized to manage neurological symptoms, formulated to target movement disorders and to manage viral replication outcomes.

Mechanism of action

Amantadine acts as a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake, providing both antiparkinsonian and antiviral effects.

Pregnancy and breastfeeding

Pregnancy: Use only if the potential benefit justifies the potential risk to the foetus. Breastfeeding: Not recommended as it enters breast milk.

Amantadine Tablets

Utilized to manage neurological symptoms, formulated to target movement disorders and to manage viral replication outcomes.

Editorial Notes

  • Active ingredient(s): Amantadine
  • Listed indication(s): Parkinson’s Disease, Influenza A

Available option

  • 120 tablets - 100 mg1209-100-mg-14354