Mirapex
Indicated to manage Parkinson's disease, this dopamine agonist is designed to alleviate motor symptoms and support movement control in affected individuals.
Strengths: 0.125 · 0.25 · 0.5mg
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Medicine details
- Alternative names
Mirapexin
- Therapeutic class
Dopamine Agonist
- Pharmacological class
Non-ergot Dopamine Agonist
- Contraindications
hypersensitivity to pramipexole
- Minor side effects
nausea; dizziness; somnolence; insomnia
- Moderate side effects
constipation; hallucinations; peripheral oedema
- Serious side effects
impulse control disorders — requires immediate medical attention
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Boehringer Ingelheim
- Onset Time
1–3 hours
- Duration
8–12 hours
- Storage instructions
Store in a cool, dry place away from light.
- Drug interactions
antipsychotics; cimetidine
- Age restrictions
Not for paediatric use.
Precautions and warnings
monitor for impulsive behaviour; may cause sudden onset of sleep; use with caution in cardiovascular disease
Patient summary
Indicated to manage Parkinson's disease, this dopamine agonist is designed to alleviate motor symptoms and support movement control in affected individuals.
Mechanism of action
Pramipexole is a non-ergot dopamine agonist that binds with high selectivity to the D2 subfamily of dopamine receptors in the striatum, helping mimic endogenous dopamine action.
Pregnancy and breastfeeding
Pregnancy: Caution advised. Breastfeeding: Not recommended as it may inhibit lactation.
Mirapex
Indicated to manage Parkinson’s disease, this dopamine agonist is designed to alleviate motor symptoms and support movement control in affected individuals.
Editorial Notes
- Active ingredient(s): Pramipexole
- Listed indication(s): Parkinson’s Disease, Restless Legs Syndrome
Usually available as
- 90 tablets - 0.25 mg143-0-25-mg-15605
- 60 tablets - 0.5 mg143-0-5-mg-15608