Alfacalcidol Capsules
Developed to support calcium metabolism and indicated to alleviate bone mineralization disorders.
Strengths: 0.25 · 0.5mcg
Where to Check Availability
Medicine details
- Alternative names
One-Alpha
- Therapeutic class
Vitamin D Analogue
- Pharmacological class
Vitamin D Analogue
- Contraindications
hypercalcaemia; metastatic calcification; hypersensitivity to alfacalcidol
- Minor side effects
nausea; constipation; diarrhoea; headache
- Moderate side effects
hypercalcaemia; hypercalciuria; fatigue; polyuria
- Dosage forms
Capsule, soft
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
LEO Pharma
- Onset Time
1–2 weeks
- Duration
24–48 hours
- Storage instructions
Store below 25°C in a cool, dry place.
- Drug interactions
calcium supplements; thiazide diuretics; digoxin
- Age restrictions
Use under medical supervision for patients of all ages.
Precautions and warnings
monitor plasma calcium levels regularly; maintain adequate phosphate intake; monitor renal function
Serious side effects
nephrocalcinosis — requires immediate medical attention; cardiac arrhythmia — requires immediate medical attention
Patient summary
Developed to support calcium metabolism and indicated to alleviate bone mineralization disorders.
Mechanism of action
Alfacalcidol is rapidly converted in the liver to calcitriol, the active form of vitamin D, which promotes calcium absorption in the gut and regulates bone mineral density.
Pregnancy and breastfeeding
Pregnancy: Use only if clearly necessary, monitor calcium. Breastfeeding: Consult a physician.
Alfacalcidol Capsules
Developed to support calcium metabolism and indicated to alleviate bone mineralization disorders.
Editorial Notes
- Active ingredient(s): Alfacalcidol
- Listed indication(s): Osteodystrophy, Hypoparathyroidism, Rickets, Osteomalacia
Usually available as
- 180 capsules - 0.25 mcg1259-0-25-mcg-15037
- 120 capsules - 0.5 mcg1259-0-5-mcg-15030