Fosamax
Designed to mitigate bone density loss in osteoporosis, indicated to support bone structural integrity and reduce the risk of fractures.
Strengths: 35 · 70mg
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Medicine details
- Conditions
- Alternative names
Fosamax Once Weekly
- Therapeutic class
Bisphosphonate
- Pharmacological class
Bisphosphonate
- Minor side effects
abdominal pain; dyspepsia; musculoskeletal pain
- Moderate side effects
oesophageal ulceration; osteonecrosis of the jaw
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Merck Sharp & Dohme
- Onset Time
3–6 months
- Duration
long term
- Storage instructions
Store at room temperature in original packaging.
- Drug interactions
Calcium supplements; antacids; iron supplements
- Age restrictions
Not indicated for use in children.
- Pregnancy and breastfeeding
Not recommended during pregnancy or breastfeeding.
Contraindications
oesophageal abnormalities; inability to stand or sit upright for 30 minutes; hypocalcaemia
Precautions and warnings
must be taken on an empty stomach with a large glass of water; stay upright for at least 30 minutes after taking; maintain adequate calcium and vitamin D intake
Serious side effects
oesophageal perforation — requires immediate medical attention; severe bone pain — requires immediate medical attention; anaphylaxis — requires immediate medical attention
Patient summary
Designed to mitigate bone density loss in osteoporosis, indicated to support bone structural integrity and reduce the risk of fractures.
Mechanism of action
Alendronate is a bisphosphonate that inhibits osteoclast-mediated bone resorption. By binding to hydroxyapatite crystals in bone, it reduces the activity of cells that break down bone tissue, thereby increasing bone mineral density.
Fosamax
Designed to mitigate bone density loss in osteoporosis, indicated to support bone structural integrity and reduce the risk of fractures.
Editorial Notes
- Active ingredient(s): Alendronate
- Listed indication(s): Osteoporosis
Usually available as
- 36 tablets - 35 mg226-35-mg-3017
- 24 tablets - 70 mg226-70-mg-3023