Alendronate Tablets
Utilized to manage osteoporosis to support bone density.
Strengths: 35 · 70mg
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Medicine details
- Conditions
- Alternative names
Fosamax
- Therapeutic class
Bisphosphonate
- Pharmacological class
Bisphosphonate
- Minor side effects
abdominal pain; dyspepsia; musculoskeletal pain
- Moderate side effects
oesophageal ulceration; gastritis
- Dosage forms
Tablet
- Administration route
Oral use
- Patient summary
Utilized to manage osteoporosis to support bone density.
- Prescription status
POM
- Manufacturer
Merck Sharp & Dohme
- Onset Time
Clinical effect is cumulative over weeks
- Duration
Long-term
- Storage instructions
Store at room temperature. Keep out of reach of children.
- Drug interactions
calcium supplements; antacids; iron preparations
- Age restrictions
Not indicated for paediatric use.
- Pregnancy and breastfeeding
Pregnancy: Not intended for use. Breastfeeding: Not recommended.
Contraindications
hypersensitivity to alendronate; oesophageal abnormalities; inability to sit or stand upright for thirty minutes
Precautions and warnings
must be taken on an empty stomach with plain water; do not lie down after administration; maintain adequate calcium and vitamin D
Serious side effects
osteonecrosis of the jaw — requires immediate medical attention; atypical femoral fracture — requires immediate medical attention
Mechanism of action
Alendronic acid is a bisphosphonate that inhibits osteoclast-mediated bone resorption. By binding to hydroxyapatite crystals in bone, it prevents bone breakdown, thereby increasing bone mass and reducing fracture risk.
Alendronate Tablets
Utilized to manage osteoporosis to support bone density.
Editorial Notes
- Active ingredient(s): Alendronic Acid
- Listed indication(s): Osteoporosis
Usually available as
- 36 tablets - 35 mg1224-35-mg-14584
- 24 tablets - 70 mg1224-70-mg-14589