Toprol Xl
developed to target cardiac excitability, reducing workload on the heart.
Strengths: 25 · 50 · 100mg
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Medicine details
- Alternative names
Betaloc SA; Lopresor
- Therapeutic class
Beta Blocker
- Pharmacological class
Beta-1 blocker
- Minor side effects
fatigue; dizziness; cold extremities
- Moderate side effects
bradycardia; sleep disturbances; depression
- Dosage forms
Modified-release tablet
- Administration route
Oral use
- Patient summary
developed to target cardiac excitability, reducing workload on the heart.
- Prescription status
POM
- Manufacturer
AstraZeneca
- Onset Time
1–2 hours
- Duration
12–24 hours
- Storage instructions
Store below 25°C in a dry place.
- Drug interactions
calcium channel blockers; cimetidine
- Age restrictions
Safe for use in children with specific monitoring.
Contraindications
hypersensitivity to beta blockers; bradycardia; severe asthma; uncompensated heart failure
Precautions and warnings
do not stop taking abruptly; may mask signs of hypoglycaemia; report shortness of breath immediately
Serious side effects
heart block — requires immediate medical attention; bronchospasm — requires immediate medical attention
Mechanism of action
Toprol Xl is a cardioselective beta-1 receptor blocker. By preventing catecholamine binding at these receptor sites in the heart, it lowers the force and rate of myocardial contraction and reduces blood pressure, decreasing the heart's oxygen demand.
Pregnancy and breastfeeding
Pregnancy: Use only if benefits justify risks. Breastfeeding: Monitor nursing infant for potential pharmacological effects.
Toprol Xl
developed to target cardiac excitability, reducing workload on the heart.
Editorial Notes
- Active ingredient(s): Metoprolol
- Listed indication(s): Hypertension, Angina Pectoris, Myocardial Infarction Prophylaxis
Usually available as
- 90 tablets - 50 mg667-50-mg-4379
- 60 tablets - 100 mg667-100-mg-4381