Protopic
Designed to alleviate atopic dermatitis symptoms, formulated to target skin inflammation and to support to manage flare-ups.
Strengths: 0.03 · 0.1%
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Medicine details
- Conditions
- Alternative names
Prograf; Adoport
- Therapeutic class
Calcineurin inhibitor
- Pharmacological class
Immunosuppressant
- Contraindications
hypersensitivity to tacrolimus; netherton syndrome
- Minor side effects
application site burning; pruritus; erythema
- Moderate side effects
folliculitis; skin infections; acne
- Serious side effects
malignancy — requires immediate medical attention
- Dosage forms
Ointment
- Administration route
Cutaneous use
- Prescription status
POM
- Manufacturer
Leo Laboratories
- Onset Time
1 week
- Duration
As directed by physician
- Storage instructions
Store below 25°C.
- Age restrictions
Not for children under 2 years.
Precautions and warnings
avoid alcohol consumption during treatment; minimize exposure to natural or artificial sunlight
Patient summary
Designed to alleviate atopic dermatitis symptoms, formulated to target skin inflammation and to support to manage flare-ups.
Mechanism of action
Tacrolimus inhibits calcineurin, a phosphatase involved in T-lymphocyte activation. By preventing calcineurin activity, it suppresses the transcription of proinflammatory cytokines, thereby reducing inflammation and skin lesions.
Pregnancy and breastfeeding
Pregnancy: Monitor closely; use only if benefit justifies risk. Breastfeeding: Use with caution; consult clinical guidance.
Protopic
Designed to alleviate atopic dermatitis symptoms, formulated to target skin inflammation and to support to manage flare-ups.
Editorial Notes
- Active ingredient(s): Tacrolimus
- Listed indication(s): Atopic Dermatitis
Available option
- 3 tubes - 0.1 %1196-0-1-pct-14168