Sitagliptin Tablets

utilized to target blood glucose levels in type 2 diabetes mellitus to support metabolic control.

Strengths: 50 · 100mg

Medicine details

Alternative names

Januvia

Therapeutic class

Dipeptidyl Peptidase-4 (DPP-4) Inhibitor

Pharmacological class

Dipeptidyl Peptidase-4 Inhibitor

Contraindications

hypersensitivity to sitagliptin

Precautions and warnings

monitor for signs of pancreatitis; use with caution in renal impairment

Minor side effects

nasopharyngitis; upper respiratory tract infection; headache

Moderate side effects

hypoglycaemia

Dosage forms

Film-coated tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Merck Sharp & Dohme

Onset Time

1–2 weeks

Duration

24 hours

Storage instructions

Store at room temperature away from high humidity.

Drug interactions

digoxin

Age restrictions

Not recommended for those under 18 years.

Serious side effects

acute pancreatitis — requires immediate medical attention; anaphylaxis — requires immediate medical attention

Patient summary

utilized to target blood glucose levels in type 2 diabetes mellitus to support metabolic control.

Mechanism of action

It serves as a selective inhibitor of the DPP-4 enzyme, which increases the levels of active incretin hormones. This mechanism encourages the body to release larger amounts of insulin and decrease glucagon production when necessary.

Pregnancy and breastfeeding

Pregnancy: Safety not established; use if potential benefit justifies risk. Breastfeeding: Consult a physician.

Sitagliptin Tablets

utilized to target blood glucose levels in type 2 diabetes mellitus to support metabolic control.

Editorial Notes

  • Active ingredient(s): Sitagliptin
  • Listed indication(s): Type 2 Diabetes Mellitus

Usually available as

  • 30 tablets - 50 mg1464-50-mg-17467
  • 30 tablets - 100 mg1464-100-mg-17473