Zoloft

Developed to alleviate symptoms of depression and anxiety, designed to support emotional stability and improve daily functioning.

Strengths: 25 · 50 · 100mg

Antidepressants icon Antidepressants Sertraline icon Sertraline

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Medicine details

Conditions
Alternative names

Lustral

Therapeutic class

Selective Serotonin Reuptake Inhibitor (SSRI)

Pharmacological class

SSRI

Minor side effects

nausea; diarrhoea; insomnia; dizziness

Moderate side effects

dry mouth; sweating; somnolence

Dosage forms

Film-coated tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Pfizer

Onset Time

2–4 weeks

Duration

long-term

Storage instructions

Store below 30°C.

Drug interactions

St. John's Wort; warfarin; NSAIDs

Age restrictions

Use with caution in paediatric populations (OCD only).

Contraindications

hypersensitivity to sertraline; concurrent use with pimozide; concurrent use of MAO inhibitors

Precautions and warnings

monitor for suicidal ideation especially in young adults; use caution in patients with history of seizures

Serious side effects

serotonin syndrome — requires immediate medical attention; suicidal ideation — requires immediate medical attention

Patient summary

Developed to alleviate symptoms of depression and anxiety, designed to support emotional stability and improve daily functioning.

Mechanism of action

Sertraline selectively inhibits the neuronal reuptake of serotonin (5-HT), resulting in increased concentrations of serotonin in the synaptic cleft, which enhances serotonergic neurotransmission and alleviates symptoms of depression and anxiety disorders.

Pregnancy and breastfeeding

Pregnancy: Consult specialist; potential risk of persistent pulmonary hypertension in newborn. Breastfeeding: Evaluate risk-benefit.

Zoloft

Developed to alleviate symptoms of depression and anxiety, designed to support emotional stability and improve daily functioning.

Editorial Notes

  • Active ingredient(s): Sertraline
  • Listed indication(s): Major Depressive Disorder, Obsessive-compulsive Disorder, Panic Disorder, Post-traumatic Stress Disorder

Usually available as

  • 270 tablets - 25 mg107-25-mg-4654
  • 120 tablets - 50 mg107-50-mg-4659
  • 120 tablets - 100 mg107-100-mg-4666