Serophene
developed to support fertility in women and indicated to target the endocrine system for improved ovulatory function.
Strengths: 25 · 50 · 100mg
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Medicine details
- Conditions
- Alternative names
Clomid
- Therapeutic class
Selective oestrogen Receptor Modulator (SERM)
- Pharmacological class
SERM
- Known off-label uses
hypogonadism
- Contraindications
pregnancy; hepatic disease; abnormal uterine bleeding; ovarian cysts
- Minor side effects
hot flushes; nausea; bloating; headache
- Moderate side effects
abdominal discomfort; breast tenderness; vision disturbances
- Serious side effects
ovarian hyperstimulation syndrome — requires immediate medical attention
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Sanofi
- Onset Time
5–10 days post-initiation
- Duration
cycle-dependent
- Storage instructions
Store in a light-resistant container.
- Age restrictions
Pre-menopausal adults.
- Pregnancy and breastfeeding
Do not use if pregnant.
Precautions and warnings
monitor for ovarian enlargement; multiple pregnancy risk; may affect visual acuity
Patient summary
developed to support fertility in women and indicated to target the endocrine system for improved ovulatory function.
Mechanism of action
Clomiphene acts as a selective oestrogen receptor modulator. It binds to oestrogen receptors in the hypothalamus, blocking negative feedback and stimulating the release of gonadotropins to induce ovulation.
Serophene
developed to support fertility in women and indicated to target the endocrine system for improved ovulatory function.
Editorial Notes
- Active ingredient(s): Clomiphene
- Listed indication(s): Anovulatory Infertility
Usually available as
- 360 tablets - 25 mg693-25-mg-4134
- 180 tablets - 50 mg693-50-mg-4139
- 90 tablets - 100 mg693-100-mg-1461