Roflumilast Tablets
indicated to manage inflammatory processes in the airways, utilizing enzyme inhibition to support reduction in exacerbations for patients with underlying respiratory conditions.
Strengths: 500mg
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Medicine details
- Conditions
- Alternative names
Daxas
- Therapeutic class
Phosphodiesterase-4 Inhibitor
- Pharmacological class
PDE4 Inhibitor
- Minor side effects
diarrhoea; nausea; abdominal pain
- Moderate side effects
insomnia; anxiety; weight decrease
- Dosage forms
Film-coated tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Takeda
- Onset Time
2–4 weeks
- Duration
24 hours
- Storage instructions
Store in a cool, dry place.
- Drug interactions
strong cytochrome P450 inhibitors; rifampicin
- Age restrictions
Not for use in individuals under eighteen years.
Contraindications
hypersensitivity to roflumilast; moderate to severe hepatic impairment; severe immunodeficiency; severe infection
Precautions and warnings
monitor weight regularly; use with caution in patients with history of depression; report any changes in mood
Serious side effects
suicidal ideation — requires immediate medical attention; severe hypersensitivity reaction — requires immediate medical attention
Patient summary
indicated to manage inflammatory processes in the airways, utilizing enzyme inhibition to support reduction in exacerbations for patients with underlying respiratory conditions.
Mechanism of action
A phosphodiesterase-4 inhibitor that acts by reducing inflammation within the lungs, helping to prevent obstruction and improve overall respiratory function in chronic conditions.
Pregnancy and breastfeeding
Pregnancy: Avoid use due to potential risks to the foetus. Breastfeeding: Do not use as it may pass into breast milk.
Roflumilast Tablets
indicated to manage inflammatory processes in the airways, utilizing enzyme inhibition to support reduction in exacerbations for patients with underlying respiratory conditions.
Editorial Notes
- Active ingredient(s): Roflumilast
- Listed indication(s): Chronic Obstructive Pulmonary Disease
Available option
- 90 tablets - 500 mg1242-500-mg-14818