Advair Diskus

This inhaler is developed to target chronic obstructive pulmonary disease and is indicated to alleviate airway inflammation.

Strengths: 100/50 · 250/50 · 500/50mcg

Medicine details

Alternative names

Seretide Accuhaler; Seroflo Inhaler; Advair Rotahaler

Therapeutic class

Beta2-adrenoceptor agonist and corticosteroid combination

Pharmacological class

Beta2-agonist; Corticosteroid

Contraindications

hypersensitivity to active ingredients; acute asthma attack

Minor side effects

headache; nasopharyngitis; hoarseness

Moderate side effects

oral candidiasis; tremor; muscle cramps

Dosage forms

Inhalation powder

Administration route

Inhalation use

Prescription status

POM

Manufacturer

GSK

Onset Time

Minutes

Duration

12 hours

Storage instructions

Store in a cool, dry place at room temperature.

Drug interactions

beta-blockers; ketoconazole; ritonavir

Age restrictions

Check age-specific guidance for children.

Precautions and warnings

rinse mouth after use to prevent fungal infection; monitor for systemic corticosteroid effects; avoid abrupt discontinuation

Serious side effects

paradoxical bronchospasm — requires immediate medical attention; pneumonia — requires immediate medical attention; arrhythmias — requires immediate medical attention

Patient summary

This inhaler is developed to target chronic obstructive pulmonary disease and is indicated to alleviate airway inflammation.

Mechanism of action

The combination provides two mechanisms: salmeterol acts as a long-acting beta2-agonist to induce bronchodilation by relaxing airway smooth muscle, while fluticasone is a corticosteroid that reduces airway inflammation and bronchial hyper-responsiveness.

Pregnancy and breastfeeding

Pregnancy: Use only if the benefit outweighs the risk. Breastfeeding: Contact physician.

Advair Diskus

This inhaler is developed to target chronic obstructive pulmonary disease and is indicated to alleviate airway inflammation.

Editorial Notes

  • Active ingredient(s): Salmeterol, Fluticasone
  • Listed indication(s): Asthma, Chronic Obstructive Pulmonary Disease

Usually available as

  • 1 inhaler - 100/50 mcg433-100-50-mcg-5852
  • 1 inhaler - 250/50 mcg433-250-50-mcg-5855
  • 1 inhaler - 500/50 mcg433-500-50-mcg-5858