Rifampin Tablets
intended to mitigate bacterial load, to target tuberculosis infection.
Strengths: 150 · 300 · 450 · 600mg
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Medicine details
- Conditions
- Alternative names
Rifadin; Rimactane
- Therapeutic class
Rifamycin Antibiotic
- Pharmacological class
Rifamycin
- Contraindications
hypersensitivity to rifamycins; jaundice; concurrent use of certain antivirals
- Minor side effects
nausea; diarrhoea; red-orange body fluids
- Moderate side effects
hepatotoxicity
- Dosage forms
Tablet
- Administration route
Oral use
- Patient summary
intended to mitigate bacterial load, to target tuberculosis infection.
- Prescription status
POM
- Manufacturer
Sanofi
- Onset Time
2–4 hours
- Duration
8–12 hours
- Storage instructions
Store in a cool, dry place.
- Drug interactions
oral contraceptives; warfarin; corticosteroids; antifungals
- Age restrictions
Safe for use in children with appropriate weight-based dosage.
Precautions and warnings
may cause orange discoloration of urine and fluids; liver function monitoring required; avoid soft contact lenses
Serious side effects
anaphylaxis — requires immediate medical attention; acute renal failure — requires immediate medical attention
Mechanism of action
Rifampicin inhibits bacterial ribonucleic acid polymerase, thereby suppressing deoxyribonucleic acid-dependent ribonucleic acid synthesis and causing bacterial cell death.
Pregnancy and breastfeeding
Pregnancy: Use only if essential. Breastfeeding: Present in breast milk; monitor infant.
Rifampin Tablets
intended to mitigate bacterial load, to target tuberculosis infection.
Editorial Notes
- Active ingredient(s): Rifampicin
- Listed indication(s): Tuberculosis, Meningococcal Carriage
Usually available as
- 180 tablets - 450 mg1270-450-mg-15162
- 90 tablets - 600 mg1270-600-mg-15165